Although 64-bit Windows platforms support both 64-bit and 32-bit applications, the OpenAFS Service installed on the machine must be 64-bit.  The 64-bit installer contains only 64-bit executables.  In order to support 32-bit applications that link against OpenAFS libraries it is required that a separate 32-bit OpenAFS Tools set be installed. For example, the 32-bit version of Kerberos for Windows can be used with the 32-bit OpenAFS Tools to manage AFS tokens.

OpenAFS on 64-bit Windows benefits from the lifting of the 2GB process memory restriction that is present in 32-bit Windows.   Without this restriction the AFS Cache File can become arbitrarily large limited only by available disk space.